pertpy.data.zhao_2021¶
- pertpy.data.zhao_2021()[source]¶
Multiplexed drug perturbation from freshly resected tumors.
This study combines multiplexed drug perturbation in acute slice culture from freshly resected tumors with scRNA-seq to profile transcriptome-wide drug responses in individual patients. They applied this approach to drug perturbations on slices derived from six glioblastoma (GBM) resections to identify conserved drug responses and to one additional GBM resection to identify patient-specific responses.
References
Publication: https://doi.org/10.1186/s13073-021-00894-y Obtained from scperturb: http://projects.sanderlab.org/scperturb/