pertpy.data.dixit_2016¶
- pertpy.data.dixit_2016()[source]¶
Perturb-seq: scRNA-seq with pooled CRISPR-KO perturbations.
scRNA-seq with pooled CRISPR-KO perturbations in 200,000 cells across six screens unstimulated BMDC, BMDC stimulated at 3hr, TFs in K562 at 7 and 13 days post transduction, and 13 days at a higher MOI of perturbations.
References
Dixit A, Parnas O, Li B, Chen J et al. Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens. Cell 2016 Dec 15;167(7):1853-1866.e17. DOI:https://doi.org/10.1016/j.cell.2016.11.038