pertpy.data.schraivogel_2020_tap_screen_chr11¶
- pertpy.data.schraivogel_2020_tap_screen_chr11()[source]¶
TAP-seq applied to K562 cells (only chromosome 11).
TAP-seq was applied to generate perturbation-based enhancer–target gene maps in K562 cells. They perturbed all 1,778 putatively active enhancers predicted on the basis of ENCODE data in two regions on chromosome 8 and 11, and identified effects on expressed protein-coding genes within the same regions. Thus, in each cell, 68 (chromosome 8) or 79 (chromosome 11) target genes were measured.
References
Publication: https://doi.org/10.1038/s41592-020-0837-5 Obtained from scperturb: http://projects.sanderlab.org/scperturb/