pertpy.data.stephenson_2021_subsampled

pertpy.data.stephenson_2021_subsampled()[source]

Processed 10X 5’ scRNA-seq data from PBMC of COVID-19 patients and healthy donors

The study profiled peripheral blood mononuclear cells from 90 COVID-19 patients with different disease severity and 23 healthy control donors. Here the dataset was downsampled to approx. 500 cells per donor and cells were mapped to a reference atlas of healthy PBMCs from 12 studies with scArches.

References

Stephenson, E., Reynolds, G., Botting, R. A., et al. (2021). Single-cell multi-omics analysis of the immune response in COVID-19. Nature Medicine, 27(5). https://doi.org/10.1038/s41591-021-01329-2

Return type:

AnnData

Returns:

AnnData object of scRNA-seq profiles