pertpy.data.gasperini_2019_atscale

pertpy.data.gasperini_2019_atscale()

Transcriptomics of 254974 cells of chronic K562 cells with CRISPRi perturbations.

Across two experiments, the authors used dCas9-KRAB to perturb 5,920 candidate enhancers with no strong a priori hypothesis as to their target gene(s) in 254,974 cells of chronic myelogenous leukemia cell line K562, with CRISPRi as the mode of perturbation.

References

Publication: https://doi.org/10.1016/j.cell.2018.11.029 Obtained from scperturb: http://projects.sanderlab.org/scperturb/

Return type:

AnnData

Returns:

AnnData object of scPerturb prepared single-cell perturbation data