pertpy.data.mcfarland_2020¶
- pertpy.data.mcfarland_2020()[source]¶
Response of various cell lines to a range of different drugs and CRISPRi perturbations.
Here, the authors developed MIX-Seq, a method for multiplexed transcriptional profiling of post-perturbation responses across many cell contexts, using scRNA-seq applied to co-treated pools of cancer cell lines. The responses of pools of 24–99 cell lines to a range of different drugs were profiled, as well as to CRISPR perturbations.
References
Publication: https://doi.org/10.1038/s41467-020-17440-w Obtained from scperturb: http://projects.sanderlab.org/scperturb/