pertpy.data.srivatsan_2020_sciplex3

pertpy.data.srivatsan_2020_sciplex3()

Transcriptomes of 650000 A549, K562, and mCF7 cells exposed to 188 compounds.

sci-Plex was used to screen three well-characterized human cancer cell lines, A549 (lung adenocarcinoma), K562 (chronic myelogenous leukemia), and MCF7 (mammary adenocarcinoma)exposed to 188 compounds, profiling ~650,000 single-cell transcriptomes across ~5000 independent samples in one experiment.

References

Publication: https://doi.org/10.1126/science.aax6234 Obtained from scperturb: http://projects.sanderlab.org/scperturb/

Return type:

AnnData

Returns:

AnnData object of scPerturb prepared single-cell perturbation data