pertpy.data.sciplex_gxe1

Contents

pertpy.data.sciplex_gxe1#

sciplex_gxe1()[source]#

sci-Plex-GxE profiling of A172 dCas9-KRAB (HPRT1 or MMR knockout) with 6-TG/TMZ and A172 dCas9-SunTag (HPRT1 knockout) with 6-TG.

References

McFaline-Figueroa JL et al., Trapnell C. Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy. Cell Genomics. 2024 Volume 4, Issue 2. doi: 10.1016/j.xgen.2023.100487

Return type:

AnnData

Returns:

AnnData object of the dataset.